Posted By Posting
Jun 05, 2009
mommy2d&h
Switching PPI's
Hi everyone, Just a quick question about switching PPI's. Yesterday we switched from Prevacid solutabs to compounded Prilosec. My son has been SO fussy and in pain. I called the GI to see if this is break-through reflux pain, etc., but she didn't give me much to go on - just said to continue through the weekend and call on Monday if things aren't better. Is this common when switching from one PPI to another, or is this a sign that Prilosec is not for him?
Jun 05, 2009
johnniesnewmommy
I am the expert on switching PPI's. I have been through them all. ;} My LO always has a hard time switching meds- it seems like it takes at least a week to start leveling out and most of the time a couple weeks before I know if its really working. Hang in there. You may also try giving mylanta as well for the next few days until the meds take over.
Jun 05, 2009
mommy2k
It could be that the prilosec isn't compounded correctly which can happen at the pharmacy. We haven't had that problem yet. I know that when we switched from prilosec to prevacid Kody got extremely fussy and it wasn't working for him. He was miserable on it so we knew that it wasn't the drug for him. Some kids do better on one and not another. Why was he switched to prilosec? I would give it a little longer. I think that the drugs just need to work themselves out in their systems. Oh and what dose is he on? It could be that his dose isn't high enough either. My ped always underdosed my son which didn't give him enough relief when we got to the gi, the doses were raised. Hang in there! I hope things get better and he starts feeling better for you. I kow how hard it is and especially on a weekend. I just had one of those weekends last week. It was rough but I was glad to have this group to get through it.
Jun 06, 2009
kubicki5
Julie - I have three children. My youngest Katie is my refluxer. My first Ben was very colicy and is ADHD. My middle Jakob is pretty easy going. Katie had it bad as a baby no sleep for two years. She was on Nutramagin, Prevacid and Zantac. Thought we were through it but after age three it came back big time. After her scope she was put on Prevacid 45mg a day and mylanta as needed. Scope was in Sept. Showed damage in stomach and espophogus. It took about 7 months of medication and Reflux diet for her to start feeling better.
Mylanta, mylanta, mylanta :)
Jun 06, 2009
slimfast13
This is our dd, Alessandra. Dx with GER 10/07. Ran the gamut with meds and now done with them (crossed fingers). Using magnesium, probiotics and prebiotic supplements. With the exception of teething and general sassy attitude, all is well now. They really CAN grow out of it!
Agree with them all. Med switches are annoying, because you tend to slide backward for at least a week, often more. And the prilosec needs to be compounded correctly (the key is finding a true compouding pharmacy - many hospitals have them, or I go to one called Medicap which has locations in many states.) The coupound is only good for 30 days even when done correctly. We did the solutabs for prevacid, but had compounded Pepcid and we always noticed that at the 3 week mark, my dd would go downhill. But ins won't cover more than a once a month fill. I theorized that the meds are breaking down and the rate kids metabolize meds made them useless after 21 days, even though the manufacturer states it's good for 30 (yeah, for ADULTS!)

I would also ask the pharmacy or MD about Maalox or Mylanta for breakthrough pain temporarily and get the correct dosage for his age and weight.

Jun 07, 2009
jeddsmommy
Jessica, Mommy to Jedd, severe reflux, severe food and oral aversions, Finally G tube free!!! VSD repair 4-24-07 (open heart surgery), hypospadias, repaired 3 times and Ear tubes Visit Jedd at his CB site: www.caringbridge.org/visit/jedd
May I ask why you want to switch??

We used a compound only because we had to, we had no choice. Jedd needed to use Prilosec compounded so it would do down his feeding tube. NONE of the other meds worked, we tried.

the thing is, compounded meds are really hard to make properly and can cause a host of stabilization issues if not made right.

Just my two cents.

Jun 07, 2009
mommy2d&h
Thanks, ladies, for your responses. Things seem to be going a little better now, so I am hopeful that things will continue to improve... We decided to switch from Prevacid because he had been on it for a couple months and I didn't feel like we were seeing much improvement. Also, my son is MPI, and I had read on this forum that sometimes MPI kids don't tolerate the Prevacid as well with the lactose component.
Jun 07, 2009
jeddsmommy
Jessica, Mommy to Jedd, severe reflux, severe food and oral aversions, Finally G tube free!!! VSD repair 4-24-07 (open heart surgery), hypospadias, repaired 3 times and Ear tubes Visit Jedd at his CB site: www.caringbridge.org/visit/jedd
You may want to make sure that whatever is being used to suspend it doens't have any MSPI things in it though. That can sometimes be an issue with other meds, I have NO idea about the suspension of Prilosec though.

I will tell you though, that the suspensions of Prilosec can be very unstable. Make sure you get it from a VERY good pharmacy that makes suspensions all the time. We got ours made at our children's hosptial.

You'll also need to make sure you get a high enough dose too.

Check with your
doctor first!