Posted By Posting
Jul 24, 2003
Singulair for reflux?
We recently returned from a follow up visit at Mayo Clinic to reevaluate my sons (4 years old) gastroesophageal reflux. A nasal endoscopy revealed negative changes of the upper esophagus and vocal cords (the beginning of nodules). This same test done last year did not show this damage. The following test, an endoscopy showed no esophagitis in the rest of the esophagus and no other abnormalities. With this information and my sons symptoms (frequent night waking, hoarse voice, stomach pain, feeding difficulties, discomfort etc.)they believed that his current medication is not effective (Nexium and Erythromycin for motility) and changed us to Aciphex and upped the dose of the Erythromycin and continued with the Miralax for constipation. It has been a month and we are seeing minimal changes. Our Gastroenterologist at home recommended to add Singulair, a med used for asthma and allergies. He thought that maybe he has some undetected allergies attributing to the reflux. His respiratory symptoms have worsened with time, but not to the point of asthma (my daughter has asthma, so I'm familiar with it). My question after this long winded note is, has this recommendations been made to anyone else and what were the results? What is the rationale for the use of this drug for reflux? Thanks for any feedback, Nancy
Jul 25, 2003
You should contact Dr Phillips, he is a pharmacologist that changed my daughter's life. She had apnea and reflux and was on Zantac (then on Nexium, then Protonix). She also was on Singulair (it didn't seem to help) In 2 weeks of Caracream and Prevacid she was a new child. He knows about the medicines and just how they have to be given. you can email him at He will help
Jan 16, 2004
Singular for Reflux
I haven't heard of Singular being used specifically, but I have dealt with a similar situation. After what my daughter went through, I would say don't use it unless allergies are confirmed through testing. My daughter (22 months old now) was diagnosed with Reflux the week after Thanksgiving (2 months ago). The diagnosis came after she had a bronchoscopy to investigate what the cause of the recurrent croup and stridorish breathing she was experiencing. She also had the hoarse throat, the frequent night wakings, and all the other extreme discomforts of severe reflux. They suspected that something was anotomically wrong with her throat and were prepared to fix it surgically. However, thankfully, we had an awesome ENT that came across the reflux on accident; I say accident because not only were they not looking for reflux with the scope, it was never even mentioned with any of the multiple doctors my daughter saw throughout the nine months that she had croup (non-stop!). She received at least 25 doses of steroids to treat it and the suspected causes were an anotomical problem or possibly reactive airway disease. Allergies were also a possibility. After finding out about the reflux, she immediately was put on meds for reflux. Through some trial and error, we ended up with a combination of prevacid and zantac, and that has been sufficient enough to clear her airway, although it isn't a perfect treatment. My point is this: seeing damage to your child's vocal cords that wasn't there before would indicate to me that maybe the current meds aren't working well enough (which you already know), and like my daughter, the acid is traveling further up the esophagus into the vocal cords. I am not sure if you are aware, so just incase you aren't, I'll tell you that reflux can cause asthma, recurrent pneumonia, croup, ear infections, and allergy like symptoms but just be very severe reflux all along. After our children already have to be on so many different kinds of meds., I certainly wouldn't put my child on another med, that doesn't even treat reflux, without proof that he or she needed it. I would have allergy testing done first. Chelsea
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